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Statistical correction for functional metagenomic profiling of a microbial community with short NGS reads

By sequence homology search, the list of all the functions found and the counts of reads being aligned to them present the functional profile of a metagenomic sample. However, a significant obstacle has been observed in this approach due to the short read length associated with many next generation...

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Detalles Bibliográficos
Publicado en:J Appl Stat
Main Authors: Du, Ruofei, Fang, Zhide
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261491/
https://ncbi.nlm.nih.gov/pubmed/30505061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02664763.2018.1426741
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