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Statistical correction for functional metagenomic profiling of a microbial community with short NGS reads

By sequence homology search, the list of all the functions found and the counts of reads being aligned to them present the functional profile of a metagenomic sample. However, a significant obstacle has been observed in this approach due to the short read length associated with many next generation...

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Bibliografiska uppgifter
I publikationen:J Appl Stat
Huvudupphovsmän: Du, Ruofei, Fang, Zhide
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261491/
https://ncbi.nlm.nih.gov/pubmed/30505061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02664763.2018.1426741
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