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Skin Metabolite, Farnesyl Pyrophosphate, Regulates Epidermal Response to Inflammation, Oxidative Stress and Migration

Skin produces cholesterol and a wide array of sterols and non-sterol mevalonate metabolites, including isoprenoid derivative farnesyl pyrophosphate (FPP). To characterize FPP action in epidermis, we generated transcriptional profiles of primary human keratinocytes treated with zaragozic acid (ZGA),...

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Detalles Bibliográficos
Publicado en:J Cell Physiol
Autores principales: Pastar, Irena, Stojadinovic, Olivera, Sawaya, Andrew P., Stone, Rivka C., Lindley, Linsey Evan, Ojeh, Nkemcho, Vukelic, Sasa, Samuels, Herbert H., Tomic-Canic, Marjana
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261461/
https://ncbi.nlm.nih.gov/pubmed/26916741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25357
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