Zinc enhances hippocampal long-term potentiation at CA1 synapses through NR2B containing NMDA receptors

The role of zinc (Zn(2+)), a modulator of N-methyl-D-aspartate (NMDA) receptors, in regulating long-term synaptic plasticity at hippocampal CA1 synapses is poorly understood. The effects of exogenous application of Zn(2+) and of chelation of endogenous Zn(2+) were examined on long-term potentiation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sullivan, John A., Zhang, Xiao-lei, Sullivan, Arthur P., Vose, Linnea R., Moghadam, Alexander A., Fried, Victor A., Stanton, Patric K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261414/
https://ncbi.nlm.nih.gov/pubmed/30485271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205907
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