Extrathymically generated regulatory T cells establish a niche for intestinal border-dwelling bacteria and affect physiologic metabolite levels

The mammalian gut microbiota provides essential metabolites to the host and promotes the differentiation and accumulation of extrathymically generated regulatory T (pTreg) cells. To explore the impact of these cells on intestinal microbial communities, we assessed the composition of the microbiota i...

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Udgivet i:Immunity
Main Authors: Campbell, Clarissa, Dikiy, Stanislav, Bhattarai, Shakti K., Chinen, Takatoshi, Matheis, Fanny, Calafiore, Marco, Hoyos, Beatrice, Hanash, Alan, Mucida, Daniel, Bucci, Vanni, Rudensky, Alexander Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260932/
https://ncbi.nlm.nih.gov/pubmed/29858010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.04.013
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