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Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages
Interleukin 10 (IL-10) is an anti-inflammatory cytokine that plays a critical role in the control of immune responses. However, its mechanisms of action remain poorly understood. Here, we show that IL-10 opposes the switch to the metabolic program induced by inflammatory stimuli in macrophages. Spec...
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| Publicado no: | Science |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6260791/ https://ncbi.nlm.nih.gov/pubmed/28473584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aal3535 |
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