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Inactivation of DNA repair—prospects for boosting cancer immune surveillance

The emergence of drug resistance depends on the ability of the genome of cancer cells to constantly mutate and evolve under selective pressures. The generation of new mutations is accelerated when genes involved in DNA repair pathways are altered. Notably, although the emergence of new mutations fos...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Genome Med
Päätekijät: Truini, Anna, Germano, Giovanni, Bardelli, Alberto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260742/
https://ncbi.nlm.nih.gov/pubmed/30486892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0603-9
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