Linking single-cell measurements of mass, growth rate, and gene expression

Mass and growth rate are highly integrative measures of cell physiology not discernable via genomic measurements. Here, we introduce a microfluidic platform enabling direct measurement of single-cell mass and growth rate upstream of highly multiplexed single-cell profiling such as single-cell RNA se...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Kimmerling, Robert J., Prakadan, Sanjay M., Gupta, Alejandro J., Calistri, Nicholas L., Stevens, Mark M., Olcum, Selim, Cermak, Nathan, Drake, Riley S., Pelton, Kristine, De Smet, Frederik, Ligon, Keith L., Shalek, Alex K., Manalis, Scott R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260722/
https://ncbi.nlm.nih.gov/pubmed/30482222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1576-0
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