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Linking single-cell measurements of mass, growth rate, and gene expression

Mass and growth rate are highly integrative measures of cell physiology not discernable via genomic measurements. Here, we introduce a microfluidic platform enabling direct measurement of single-cell mass and growth rate upstream of highly multiplexed single-cell profiling such as single-cell RNA se...

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Библиографические подробности
Опубликовано в: :Genome Biol
Главные авторы: Kimmerling, Robert J., Prakadan, Sanjay M., Gupta, Alejandro J., Calistri, Nicholas L., Stevens, Mark M., Olcum, Selim, Cermak, Nathan, Drake, Riley S., Pelton, Kristine, De Smet, Frederik, Ligon, Keith L., Shalek, Alex K., Manalis, Scott R.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260722/
https://ncbi.nlm.nih.gov/pubmed/30482222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1576-0
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