Linking single-cell measurements of mass, growth rate, and gene expression

Mass and growth rate are highly integrative measures of cell physiology not discernable via genomic measurements. Here, we introduce a microfluidic platform enabling direct measurement of single-cell mass and growth rate upstream of highly multiplexed single-cell profiling such as single-cell RNA se...

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Dettagli Bibliografici
Pubblicato in:Genome Biol
Autori principali: Kimmerling, Robert J., Prakadan, Sanjay M., Gupta, Alejandro J., Calistri, Nicholas L., Stevens, Mark M., Olcum, Selim, Cermak, Nathan, Drake, Riley S., Pelton, Kristine, De Smet, Frederik, Ligon, Keith L., Shalek, Alex K., Manalis, Scott R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Method
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260722/
https://ncbi.nlm.nih.gov/pubmed/30482222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1576-0
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