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Multi-arm multi-stage trials can improve the efficiency of finding effective treatments for stroke: a case study

BACKGROUND: Many recent Stroke trials fail to show a beneficial effect of the intervention late in the development. Currently a large number of new treatment options are being developed. Multi-arm multi-stage (MAMS) designs offer one potential strategy to avoid lengthy studies of treatments without...

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Библиографические подробности
Опубликовано в: :BMC Cardiovasc Disord
Главные авторы: Jaki, Thomas, Wason, James M. S.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260683/
https://ncbi.nlm.nih.gov/pubmed/30482176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-018-0956-4
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