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Heteroplasmy Detection of Mitochondrial DNA A3243G Mutation Using Quantitative Real-Time PCR Assay Based on TaqMan-MGB Probes

A point mutation of mitochondrial DNA (mtDNA) at nucleotide position 3243 A to G (mt.3243A>G) is involved in many common diseases, including maternally inherited diabetes and deafness (MIDD) and mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes (MELAS). However, the mutan...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Rong, Enguang, Wang, Hanbo, Hao, Shujing, Fu, Yuhong, Ma, Yanyan, Wang, Tianze
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260548/
https://ncbi.nlm.nih.gov/pubmed/30539000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1286480
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