Prediction of the Closed Conformation and Insights into the Mechanism of the Membrane Enzyme LpxR

Covalent modification of outer membrane lipids of Gram-negative bacteria can impact the ability of the bacterium to develop resistance to antibiotics as well as modulating the immune response of the host. The enzyme LpxR from Salmonella typhimurium is known to deacylate lipopolysaccharide molecules...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biophys J
Egile Nagusiak: Saunders, Graham M., Bruce Macdonald, Hannah E., Essex, Jonathan W., Khalid, Syma
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2018
Gaiak:
Proteins
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260217/
https://ncbi.nlm.nih.gov/pubmed/30287112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.09.002
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