A characteristic signature of insulin-like growth factor (IGF) axis expression during osteogenic differentiation of human dental pulp cells (hDPCs): Potential co-ordinated regulation of IGF action

The IGF axis is represented by two growth factors (IGF1 and IGF2), two cognate cell surface receptors (IGF1R and IGF2R), six soluble high affinity IGF binding proteins (IGFBP1-6) and several IGFBP proteases. IGF1 and IGF2 are present at high concentrations in bone and play a crucial role in the main...

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Detalhes bibliográficos
Publicado no:Growth Horm IGF Res
Main Authors: Al-Khafaji, Hasanain, Noer, Pernille R., Alkharobi, Hanna, Alhodhodi, Aishah, Meade, Josephine, El-Gendy, Reem, Oxvig, Claus, Beattie, James
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259625/
https://ncbi.nlm.nih.gov/pubmed/30071469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2018.07.003
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