Reduction of Diphenyl Diselenide and Analogs by Mammalian Thioredoxin Reductase Is Independent of Their Gluthathione Peroxidase-Like Activity: A Possible Novel Pathway for Their Antioxidant Activity

Since the successful use of the organoselenium drug ebselen in clinical trials for the treatment of neuropathological conditions associated with oxidative stress, there have been concerted efforts geared towards understanding the precise mechanism of action of ebselen and other organoselenium compou...

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Pubblicato in:Molecules
Autori principali: de Freitas, Andressa Sausen, Prestes, Alessandro de Souza, Wagner, Caroline, Sudati, Jéssie Haigert, Alves, Diego, Porciúncula, Lisiane Oliveira, Kade, Ige Joseph, Rocha, João Batista Teixeira
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259470/
https://ncbi.nlm.nih.gov/pubmed/21030914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15117699
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