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Reduction of Diphenyl Diselenide and Analogs by Mammalian Thioredoxin Reductase Is Independent of Their Gluthathione Peroxidase-Like Activity: A Possible Novel Pathway for Their Antioxidant Activity

Since the successful use of the organoselenium drug ebselen in clinical trials for the treatment of neuropathological conditions associated with oxidative stress, there have been concerted efforts geared towards understanding the precise mechanism of action of ebselen and other organoselenium compou...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: de Freitas, Andressa Sausen, Prestes, Alessandro de Souza, Wagner, Caroline, Sudati, Jéssie Haigert, Alves, Diego, Porciúncula, Lisiane Oliveira, Kade, Ige Joseph, Rocha, João Batista Teixeira
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259470/
https://ncbi.nlm.nih.gov/pubmed/21030914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15117699
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