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Peptide Phage Display as a Tool for Drug Discovery: Targeting Membrane Receptors

Ligands selected from phage-displayed random peptide libraries tend to be directed to biologically relevant sites on the surface of the target protein. Consequently, peptides derived from library screenings often modulate the target protein’s activity in vitro and in vivo and can be used as lead com...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Molek, Peter, Strukelj, Borut, Bratkovic, Tomaz
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259427/
https://ncbi.nlm.nih.gov/pubmed/21258295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16010857
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