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Peptide Phage Display as a Tool for Drug Discovery: Targeting Membrane Receptors

Ligands selected from phage-displayed random peptide libraries tend to be directed to biologically relevant sites on the surface of the target protein. Consequently, peptides derived from library screenings often modulate the target protein’s activity in vitro and in vivo and can be used as lead com...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Molek, Peter, Strukelj, Borut, Bratkovic, Tomaz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259427/
https://ncbi.nlm.nih.gov/pubmed/21258295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16010857
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