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Synthesis and Structure-Activity Relationships of Fenbufen Amide Analogs

The previous discoveries of butyl fenbufen amide analogs with antitumor effects were further examined. The amide analogs with 1, 3, 4 and 8 carbons chains were prepared in 70–80% yield. Fenbufen had no cytotoxic effects at concentrations ranging from 10 to 100 μM. Methyl fenbufen amide had significa...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Lin, Kun-I, Yang, Chao-Hsun, Huang, Chia-Wen, Jian, Jhen-Yi, Huang, Yu-Chun, Yu, Chung-Shan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259210/
https://ncbi.nlm.nih.gov/pubmed/21127465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15128796
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