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Synthesis and Structure-Activity Relationships of Fenbufen Amide Analogs

The previous discoveries of butyl fenbufen amide analogs with antitumor effects were further examined. The amide analogs with 1, 3, 4 and 8 carbons chains were prepared in 70–80% yield. Fenbufen had no cytotoxic effects at concentrations ranging from 10 to 100 μM. Methyl fenbufen amide had significa...

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Publicado en:Molecules
Main Authors: Lin, Kun-I, Yang, Chao-Hsun, Huang, Chia-Wen, Jian, Jhen-Yi, Huang, Yu-Chun, Yu, Chung-Shan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259210/
https://ncbi.nlm.nih.gov/pubmed/21127465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15128796
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