Synthesis of Oligodeoxynucleotides Using Fully Protected Deoxynucleoside 3′-Phosphoramidite Building Blocks and Base Recognition of Oligodeoxynucleotides Incorporating N(3)-Cyano-Ethylthymine

Oligodeoxynucleotide (ODN) synthesis, which avoids the formation of side products, is of great importance to biochemistry-based technology development. One side reaction of ODN synthesis is the cyanoethylation of the nucleobases. We suppressed this reaction by synthesizing ODNs using fully protected...

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Publicado en:Molecules
Autores principales: Tsunoda, Hirosuke, Kudo, Tomomi, Ohkubo, Akihiro, Seio, Kohji, Sekine, Mitsuo
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259151/
https://ncbi.nlm.nih.gov/pubmed/21030906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15117509
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