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The Abundant Tegument Protein pUL25 of Human Cytomegalovirus Prevents Proteasomal Degradation of pUL26 and Supports Its Suppression of ISGylation

The tegument of human cytomegalovirus (HCMV) virions contains proteins that interfere with both the intrinsic and the innate immunity. One protein with a thus far unknown function is pUL25. The deletion of pUL25 in a viral mutant (Towne-ΔUL25) had no impact on the release of virions and subviral den...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zimmermann, Christine, Büscher, Nicole, Krauter, Steffi, Krämer, Nadine, Wolfrum, Uwe, Sehn, Elisabeth, Tenzer, Stefan, Plachter, Bodo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258951/
https://ncbi.nlm.nih.gov/pubmed/30282718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01180-18
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