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Efficient Induction of T Cells against Conserved HIV-1 Regions by Mosaic Vaccines Delivered as Self-Amplifying mRNA
Focusing T cell responses on the most vulnerable parts of HIV-1, the functionally conserved regions of HIV-1 proteins, is likely a key prerequisite for vaccine success. For a T cell vaccine to efficiently control HIV-1 replication, the vaccine-elicited individual CD8(+) T cells and as a population h...
Zapisane w:
| Wydane w: | Mol Ther Methods Clin Dev |
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| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Gene & Cell Therapy
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6258890/ https://ncbi.nlm.nih.gov/pubmed/30547051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.10.010 |
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