Lentiviral Vector Purification Using Genetically Encoded Biotin Mimic in Packaging Cell

Lentiviral vectors (LVs) have recently witnessed an increasing demand in research and clinical applications. Their current purification processes represent the main bottleneck in their widespread use, as the methods used are cumbersome and yield low recoveries. We aimed to develop a one-step method...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Mekkaoui, Leila, Parekh, Farhaan, Kotsopoulou, Ekaterini, Darling, David, Dickson, Glenda, Cheung, Gordon W., Chan, Lucas, MacLellan-Gibson, Kirsty, Mattiuzzo, Giada, Farzaneh, Farzin, Takeuchi, Yasuhiro., Pule, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258877/
https://ncbi.nlm.nih.gov/pubmed/30547049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.10.008
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