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Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant

The function of Retinoblastoma tumor suppressor (pRB) is greatly influenced by the cellular context, therefore the consequences of pRB inactivation are cell-type-specific. Here we employ single cell RNA-sequencing (scRNA-seq) to profile the impact of an Rbf mutation during Drosophila eye development...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Ariss, Majd M., Islam, Abul B. M. M. K., Critcher, Meg, Zappia, Maria Paula, Frolov, Maxim V.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258665/
https://ncbi.nlm.nih.gov/pubmed/30479347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07540-z
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