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Universal CARs, universal T cells, and universal CAR T cells

Currently, the two approved T cell products with chimeric antigen receptors (CAR) are from autologous T cells. These CAR T cells approved for clinical use must be generated on a custom-made basis. This case-by-case autologous T cell production platform remains a significant limiting factor for large...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Zhao, Juanjuan, Lin, Quande, Song, Yongping, Liu, Delong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257951/
https://ncbi.nlm.nih.gov/pubmed/30482221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0677-2
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