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Crosstalk between mitogen-activated protein kinase inhibitors and transforming growth factor-β signaling results in variable activation of human dermal fibroblasts

Fibroblast activation is a key step in the establishment of skin fibrosis induced by acute injury, and it is characterized by the differentiation of plastic resident tissue fibroblasts into contractile, extracellular matrix-secreting myofibroblasts. As fibroblast activation must be regulated in vivo...

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Vydáno v:Int J Mol Med
Hlavní autoři: Dolivo, David M., Larson, Sara A., Dominko, Tanja
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257852/
https://ncbi.nlm.nih.gov/pubmed/30365043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3949
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