An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-α,β-unsaturated Esters

A microwave-assisted HWE olefination process of readily accessible aryl-alkyl ketones has been developed to provide a rapid access to (Z)-3,3-trisubstituted-α,β-unsaturated methyl esters, key building blocks for the synthesis of biologically active compounds.

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Bibliographic Details
Published in:	Molecules
Main Authors:	Rossi, Daniela, Baraglia, Anna Carnevale, Serra, Massimo, Azzolina, Ornella, Collina, Simona
Format:	Artigo
Language:	Inglês
Published:	MDPI 2010
Subjects:	Communication
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6257757/ https://ncbi.nlm.nih.gov/pubmed/20802404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15095928
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An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-α,β-unsaturated Esters

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