Neuroprotective Effects of Herbal Ethanol Extracts from Gynostemma pentaphyllum in the 6-Hydroxydopamine-Lesioned Rat Model of Parkinson's Disease

6-Hydroxydopamine administration for 28 days (8 μg/2 μL) reduced the number of tyrosine hydroxylase (TH)-immunopositive neurons to 40.2% in the substantia nigra compared to the intact contralateral side. Dopamine, 3,4-dihydroxyphenylacetic acid, homovanillic acid and norepinephrine levels were reduc...

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Published in:Molecules
Main Authors: Choi, Hyun Sook, Park, Mi Sook, Kim, Seung Hwan, Hwang, Bang Yeon, Lee, Chong Kil, Lee, Myung Koo
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257318/
https://ncbi.nlm.nih.gov/pubmed/20428081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15042814
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