Gypenosides attenuate the development of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rat model of Parkinson’s disease

BACKGROUND: Gypenosides (GPS) and ethanol extract of Gynostemma pentaphyllum (GP-EX) show anxiolytic effects on affective disorders in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of Parkinson’s disease (PD). Long-term administration of L-3,4-dihydroxyphenylalanine (L-DOPA) lead...

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Bibliographic Details
Published in:BMC Neurosci
Main Authors: Shin, Keon Sung, Zhao, Ting Ting, Park, Keun Hong, Park, Hyun Jin, Hwang, Bang Yeon, Lee, Chong Kil, Lee, Myung Koo
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431176/
https://ncbi.nlm.nih.gov/pubmed/25896846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-015-0163-5
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