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Copper-Catalyzed N-Arylation of Amides Using (S)-N-Methylpyrrolidine-2-carboxylate as the Ligand

(S)-N-methylpyrrolidine-2-carboxylate, a derivative of natural L-proline, was found to be an efficient ligand for the copper-catalyzed Goldberg-type N-arylation of amides with aryl halides under mild conditions. A variety of N-arylamides were synthesized in good to high yields.

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Vydáno v:Molecules
Hlavní autoři: Wang, Chaoyu, Liu, Lijuan, Wang, Wei, Ma, Dong-Sheng, Zhang, Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: Molecular Diversity Preservation International 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257265/
https://ncbi.nlm.nih.gov/pubmed/20335970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15031154
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