Amixicile Reduces Severity of Cryptosporidiosis but Does Not Have In Vitro Activity against Cryptosporidium

Cryptosporidium species cause significant morbidity in malnourished children. Nitazoxanide (NTZ) is the only approved treatment for cryptosporidiosis, but NTZ has diminished effectiveness during malnutrition. Here, we show that amixicile, a highly selective water-soluble derivative of NTZ diminishes...

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Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Bartelt, Luther A., Bolick, David T., Kolling, Glynis L., Stebbins, Erin, Huston, Christopher D., Guerrant, Richard L., Hoffman, Paul S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2018
Gaiak:
Mechanisms of Action: Physiological Effects
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256802/
https://ncbi.nlm.nih.gov/pubmed/30297368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00718-18
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