Two Regulators, PA3898 and PA2100, Modulate the Pseudomonas aeruginosa Multidrug Resistance MexAB-OprM and EmrAB Efflux Pumps and Biofilm Formation

It is generally believed that the Pseudomonas aeruginosa biofilm matrix itself acts as a molecular sieve or sink that contributes to significant levels of drug resistance, but it is becoming more apparent that multidrug efflux pumps induced during biofilm growth significantly enhance resistance leve...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Heacock-Kang, Yun, Sun, Zhenxin, Zarzycki-Siek, Jan, Poonsuk, Kanchana, McMillan, Ian A., Chuanchuen, Rungtip, Hoang, Tung T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256797/
https://ncbi.nlm.nih.gov/pubmed/30297364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01459-18
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