2381. Ceftolozane/Tazobactam in the Treatment of Experimental Pseudomonas aeruginosa Pneumonia in Persistently Neutropenic Rabbits: Impact on Strains With Genetically Defined Resistance

BACKGROUND: Pseudomonas pneumonia is a life-threatening infection with high mortality, particularly in neutropenic patients. The efficacy of current antimicrobial therapy with extended spectrum penicillins (ESPs) and anti-pseudomonal cephalosporins (ASCs) is limited by emergence of resistance. Cefto...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Petraitis, Vidmantas, Petraitiene, Ruta, Naing, Ethan, Aung, Thein, Thi, Wai Phyo, Kavaliauskas, Povilas, DeRyke, C Andrew, Culshaw, Darren L, Caro, Luzelena, Satlin, Michael J, Walsh, Thomas J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255582/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.2034
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