1970. Phase 1 Clinical Trial of Intranasal Immunization with M2-Deficient, Single Replication, Live Influenza Vaccine (M2SR): Safety and Immune Response in Adults

BACKGROUND: Influenza vaccines are needed with greater effectiveness and breadth of coverage. FluGen is developing M2SR (M2 deficient Single Replication), an investigational, live virus vaccine. M2SR contains the internal proteins of donor A/Puerto Rico/8/34 and hemagglutinin (HA) and neuraminidase...

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Veröffentlicht in:Open Forum Infect Dis
Hauptverfasser: Eiden, Joseph, Gordon, Gilad, Fierro, Carlos, Belshe, Robert, Greenberg, Harry, Hoft, Dan, Hatta, Yasuko, Imboden, Michael, Moser, Mike, Herber, Renee, Boltz, David, Tary-Lehmann, Magdalena, Kawaoka, Yoshihiro, Neumann, Gabriele, Radspinner, Paul, Aitchison, Roger, Bilsel, Pamuk
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Abstracts
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254821/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1626
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