1970. Phase 1 Clinical Trial of Intranasal Immunization with M2-Deficient, Single Replication, Live Influenza Vaccine (M2SR): Safety and Immune Response in Adults

BACKGROUND: Influenza vaccines are needed with greater effectiveness and breadth of coverage. FluGen is developing M2SR (M2 deficient Single Replication), an investigational, live virus vaccine. M2SR contains the internal proteins of donor A/Puerto Rico/8/34 and hemagglutinin (HA) and neuraminidase...

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Publicado en:Open Forum Infect Dis
Autores principales: Eiden, Joseph, Gordon, Gilad, Fierro, Carlos, Belshe, Robert, Greenberg, Harry, Hoft, Dan, Hatta, Yasuko, Imboden, Michael, Moser, Mike, Herber, Renee, Boltz, David, Tary-Lehmann, Magdalena, Kawaoka, Yoshihiro, Neumann, Gabriele, Radspinner, Paul, Aitchison, Roger, Bilsel, Pamuk
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Abstracts
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254821/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1626
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