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Cell cycle localization dynamics of mitochondrial DNA polymerase IC in African trypanosomes

Trypanosoma brucei has a unique catenated mitochondrial DNA (mtDNA) network called kinetoplast DNA (kDNA). Replication of kDNA occurs once per cell cycle in near synchrony with nuclear S phase and requires the coordination of many proteins. Among these are three essential DNA polymerases (TbPOLIB, I...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Concepción-Acevedo, Jeniffer, Miller, Jonathan C., Boucher, Michael J., Klingbeil, Michele M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254582/
https://ncbi.nlm.nih.gov/pubmed/30133333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-02-0127
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