1409. Evaluation of Alternative Piperacillin–tazobactam Dosing Strategies Against ESBL-Producing Enterobacteriaceae Using a Hollowfiber Infection Model

BACKGROUND: Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae exhibit variable response to treatment with piperacillin–tazobactam. Current clinical practice with piperacillin–tazobactam involves dosing the components simultaneously at a fixed ratio of 8:1 piperacillin to tazobactam....

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Bibliographic Details
Published in:Open Forum Infect Dis
Main Authors: Abodakpi, Henrietta, Chang, Kai-Tai, Sánchez-Díaz, Ana Maria, Cantón, Rafael, Tam, Vincent
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254524/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1240
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