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A Novel Framework to Compare the Effectiveness of β-lactamase Inhibitors against Extended-Spectrum β-lactamase-producing Enterobacteriaceae

OBJECTIVES: Extended-spectrum β-lactamases (ESBLs) present a serious challenge in the treatment of Gram-negative bacterial infections. ESBLs mediate resistance to most β-lactams, which may be reversed with the addition of an active β-lactamase inhibitor (such as tazobactam, relebactam and avibactam)...

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Detalhes bibliográficos
Publicado no:Clin Microbiol Infect
Main Authors: Abodakpi, Henrietta, Chang, Kai-Tai, Zhou, Jian, Byerly, Caitlan, Tam, Vincent H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639165/
https://ncbi.nlm.nih.gov/pubmed/30664934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmi.2019.01.003
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