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The Streptococcus pyogenes Shr protein captures human hemoglobin using two structurally unique binding domains

In order to proliferate and mount an infection, many bacterial pathogens need to acquire iron from their host. The most abundant iron source in the body is the oxygen transporter hemoglobin (Hb). Streptococcus pyogenes, a potentially lethal human pathogen, uses the Shr protein to capture Hb on the c...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Macdonald, Ramsay, Cascio, Duilio, Collazo, Michael J., Phillips, Martin, Clubb, Robert T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254355/
https://ncbi.nlm.nih.gov/pubmed/30301765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005261
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