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The Streptococcus pyogenes Shr protein captures human hemoglobin using two structurally unique binding domains
In order to proliferate and mount an infection, many bacterial pathogens need to acquire iron from their host. The most abundant iron source in the body is the oxygen transporter hemoglobin (Hb). Streptococcus pyogenes, a potentially lethal human pathogen, uses the Shr protein to capture Hb on the c...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6254355/ https://ncbi.nlm.nih.gov/pubmed/30301765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005261 |
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