Structural basis of inactivation of Ras and Rap1 small GTPases by Ras/Rap1-specific endopeptidase from the sepsis-causing pathogen Vibrio vulnificus

Multifunctional autoprocessing repeats-in-toxin (MARTX) toxins are secreted by Gram-negative bacteria and function as primary virulence-promoting macromolecules that deliver multiple cytopathic and cytotoxic effector domains into the host cytoplasm. Among these effectors, Ras/Rap1-specific endopepti...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Jang, Song Yee, Hwang, Jungwon, Kim, Byoung Sik, Lee, Eun-Young, Oh, Byung-Ha, Kim, Myung Hee
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2018
Предметы:
Protein Structure and Folding
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254334/
https://ncbi.nlm.nih.gov/pubmed/30282804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004857
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