2294. Evaluation of the Karius Plasma Next-Generation Sequencing Cell-free Pathogen DNA Test to Determine the Etiology of Infection and Impact on Anti-Microbial Management in Patients with Severe Neutropenia and Fever

BACKGROUND: Standard microbiological testing (MT) fails to identify a pathogen in most chemotherapy recipients with febrile neutropenia (FN), who therefore receive prolonged empiric courses of broad-spectrum antimicrobials (AM). We evaluated the ability of the Karius next-generation sequencing plasm...

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Publicado no:Open Forum Infect Dis
Main Authors: Benamu, Esther, Gajurel, Kiran, Anderson, Jill N, Lieb, Tullia, Gomez, Carlos A, Seng, Hon, Aquino, Romielle, Hollemon, Desiree, Hong, David, Blauwkamp, Timothy, Kertesz, Mickey, Blair, Lily, Bollyky, Paul L, Medeiros, Bruno C, Coutre, Steven, Zompi, Simona, Montoya, Jose G, Deresinski, Stan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6253931/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1947
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