Performance of the Karius Plasma Next Generation Sequencing Test in Determining the Etiologic Diagnosis of Febrile Neutropenia: Results from a Pilot Study

BACKGROUND: Blood cultures (BC) fail to detect a pathogen in most patients with neutropenic fever (NF). We examined the performance of the Karius next generation sequencing plasma test (plasma NGS) compared with that of BC in chemotherapy-induced NF. METHODS: Patients 18 years or older with absolute...

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Vydáno v:Open Forum Infect Dis
Hlavní autoři: Benamu, Esther, Gajurel, Kiran, Anderson, Jill N, Seng, Hon, Hollemon, Desiree, Hong, David, Blawkamp, Timothy A, Kertesz, Mickey, Ishak, Heather, Bollyky, Paul L, Medeiros, Bruno C, Coutre, Steven, Montoya, Jose G, Deresinski, Stan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631391/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1614
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