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1401. A Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Pharmacokinetics of Single and Repeat Doses of VNRX-5133 in Healthy Subjects
BACKGROUND: VNRX-5133 is a novel, non-β-lactam, β-lactamase inhibitor with potent and selective direct inhibitory activity against serine- and metallo-β-lactamases. VNRX-5133, combined with the β-lactam antibiotic cefepime, is being developed for the treatment of serious infections due to multidrug-...
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| Publicado en: | Open Forum Infect Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6253564/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1232 |
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