2385. Ceftazidime–Avibactam in Combination With Fosfomycin: A Novel Therapeutic Strategy Against Multidrug-Resistant Pseudomonas aeruginosa

BACKGROUND: By targeting penicillin binding protein-3, the AmpC β-lactamase, and MurA, another enzyme involved in cell wall synthesis, with the ceftazidime–avibactam–fosfomycin combination, we previously overcame multidrug resistance (MDR) in vitro in an archived collection of Pseudomonas aeruginosa...

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Bibliografiske detaljer
Udgivet i:Open Forum Infect Dis
Main Authors: Papp-Wallace, Krisztina M, Zeiser, Elise T, Becka, Scott A, Park, Steven T, Winkler, Marisa L, Nguyen, Kevin, Singh, Indresh, Sutton, Granger, Fouts, Derrick E, Ellis-Grosse, Evelyn J, Drusano, George L, Perlin, David S, Bonomo, Robert A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6253269/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.2038
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