1774. Ridinilazole (RDZ) for Clostridium difficile infection (CDI): Correlation of In Vitro Spectrum of Activity with Human Gut Microbiome Profiles from a Phase 2 Clinical Trial

BACKGROUND: Recurrence of CDI (rCDI) is associated with perturbation of the gut microbiome during treatment with vancomycin (VAN) or metronidazole (MTZ). RDZ is a novel, targeted spectrum antibacterial under investigation to treat CDI and reduce rCDI. Here correlation of in vitro spectrum of activit...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Vickers, Richard, Goldstein, Ellie J C, Citron, Diane, Snydman, David, Thorpe, Cheleste M, Kane, Anne V
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252795/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy209.159
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