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1361. Pharmacokinetics and Safety of Ridinilazole (RDZ), a Potential New Therapy for Clostridium difficile Infection (CDI): From Animal Models to Patients

BACKGROUND: CDI is the leading cause of nosocomial diarrhea associated with 29,000 deaths p.a. in the United States. RDZ is a novel oral drug highly selective for C. difficile limiting collateral damage to the gut microbiota. Here we present a combined analysis of all pharmacokinetic (PK) and tolera...

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Publicat a:Open Forum Infect Dis
Autors principals: Duperchy, Esther, Chowdhury, Sumita, Vickers, Richard, Robinson, Neil
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252838/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1192
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