1584. Development and Dynamics of Cytomegalovirus UL97 Ganciclovir Resistance Mutations in Transplant Recipients Detected by Next-generation Sequencing

BACKGROUND: (Val)ganciclovir resistance mutations (GRMs) in CMV UL97 (UL97-GCV-R) complicate prophylaxis and therapy of solid-organ transplant (SOT) and hematopoietic (stem) cell transplant (HCT) recipients, but data on prevalence and dynamics are scarce. We investigated UL97-GCV-R using next-genera...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Lodding, Isabelle Paula, Jørgensen, Mette, Bennedbæk, Marc, Kirkby, Nikolai, Naegele, Klaudia, Gustafsson, Finn, Perch, Michael, Rasmussen, Allan, Sengeløv, Henrik, Sørensen, Søren Schwartz, Hirsch, Hans, Lundgren, Jens D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252745/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1412
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