PPIs Are Not Responsible for Elevating Cardiovascular Risk in Patients on Clopidogrel—A Systematic Review and Meta-Analysis

Background: Clopidogrel and proton pump inhibitors (PPIs) are metabolized by cytochrome P450 enzymes. Contradictory results have been reported on possible complications of simultaneous PPI and clopidogrel use. Our aim was to investigate the clinical relevance of this debate with a systematic review...

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Vydáno v:Front Physiol
Hlavní autoři: Demcsák, Alexandra, Lantos, Tamás, Bálint, Emese Réka, Hartmann, Petra, Vincze, Áron, Bajor, Judit, Czopf, László, Alizadeh, Hussain, Gyöngyi, Zoltán, Márta, Katalin, Mikó, Alexandra, Szakács, Zsolt, Pécsi, Dániel, Hegyi, Péter, Szabó, Imre László
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252380/
https://ncbi.nlm.nih.gov/pubmed/30510515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01550
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