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PPIs Are Not Responsible for Elevating Cardiovascular Risk in Patients on Clopidogrel—A Systematic Review and Meta-Analysis

Background: Clopidogrel and proton pump inhibitors (PPIs) are metabolized by cytochrome P450 enzymes. Contradictory results have been reported on possible complications of simultaneous PPI and clopidogrel use. Our aim was to investigate the clinical relevance of this debate with a systematic review...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Demcsák, Alexandra, Lantos, Tamás, Bálint, Emese Réka, Hartmann, Petra, Vincze, Áron, Bajor, Judit, Czopf, László, Alizadeh, Hussain, Gyöngyi, Zoltán, Márta, Katalin, Mikó, Alexandra, Szakács, Zsolt, Pécsi, Dániel, Hegyi, Péter, Szabó, Imre László
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252380/
https://ncbi.nlm.nih.gov/pubmed/30510515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01550
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