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Ligand Density and Nanoparticle Clustering Cooperate in the Multivalent Amplification of Epidermal Growth Factor Receptor Activation
Multivalent presentation of ligands on nanoparticles (NP) is considered a general strategy for enhancing receptor binding and activation through amplification of ligand-receptor interactions within the footprint of the NP. The spatial clustering of ligand-functionalized NP represents an additional,...
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| Publicado en: | ACS Nano |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6252274/ https://ncbi.nlm.nih.gov/pubmed/30289688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b06141 |
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