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Ligand Density and Nanoparticle Clustering Cooperate in the Multivalent Amplification of Epidermal Growth Factor Receptor Activation

Multivalent presentation of ligands on nanoparticles (NP) is considered a general strategy for enhancing receptor binding and activation through amplification of ligand-receptor interactions within the footprint of the NP. The spatial clustering of ligand-functionalized NP represents an additional,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Nano
Prif Awduron: Zhang, Qianyun, Reinhard, Björn M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252274/
https://ncbi.nlm.nih.gov/pubmed/30289688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b06141
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